On Demand: “Part 3: Targeting Cancer Pathways” Now Available

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Part 3: Targeting Cancer Pathways: Tumor Metabolism and Proliferation– Now Complimentary on Demand In case you missed our live, online educational seminar, “Part 3: Targeting Cancer Pathways: Tumor Metabolism and Proliferation” we wanted to let you know that it is available in our complimentary on-demand archive. You can access this archive to watch the webinar at any time. For more information and access to the archive, go to: webinar.sciencemag.org About This Webinar This webinar is the third in a series focusing on the cancer pathways that support tumor development, the emerging research in identifying and targeting these pathways, and innovations in the development of increasingly effective cancer therapy options. Recent advances in our understanding of cancer have revealed that the disease cannot be understood through simple analysis of genetic mutations within the cancerous cells. Instead, tumors should be considered as complex tissues in which the cancer cells communicate directly and indirectly with the surrounding cellular microenvironment and evolve traits that promote their own survival. In this webinar we will explore how cancer cells are able to reprogram their metabolic pathways to enable energy production under conditions that are disabling to most normal cells. Of particular interest are how tumor-specific metabolic changes promote oncogenic progression and how these changes can be exploited to develop more effective treatment options. During the webinar, the speakers will: • Outline the major metabolic changes seen in tumor tissue • Explain how specific metabolic pathways can be targeted during therapeutic interventions • Introduce the role of autophagy and cell death in tumor survival and progression • Answer your questions live during the broadcast! <!– • Have their questions answered live by the panelists! –> Participants: M. Celeste Simon, Ph.D. University of Pennsylvania Philadelphia, PA Nissim Hay, Ph.D. University of Illinois Chicago, IL <!– Giridharan Periyasamy, Ph.D. Genome Institute of Singapore Singapore, Malaysia –> Register at: webinar.sciencemag.org Questions? E-mail: webinar@aaas.org. Produced by the Science/AAAS Custom Publishing Office and sponsored by Cell Signaling.

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Table of Contents for 19 June 2015; Vol. 348, No. 6241

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Sponsored by Science & SciLifeLab Prize for Young Scientists    Want to be published in Science?    Want to receive US$30,000 for your research?    Now accepting entries    Science & SciLifeLab Prize for Young Scientists    Deadline: August 1, 2015    Visit www.sciencemag.org/scilifelabprize Science Table of Contents   06/19/15 Volume 348, Issue 6241 In this week’s issue: Research Summaries This Week in Science Editor summaries of this week’s papers. Editors’ Choice Highlights of the recent literature. Editorial Parks for science Gary Machlis and Marcia McNutt In Brief This week’s section A roundup of weekly science policy and related news. In Depth Space Science The return of Philae Eric Hand and Daniel Clery Revived after hibernation, comet lander awaits orders. Animal Research Research chimps will soon be listed as ‘endangered’ David Grimm Ruling could disrupt biomedical research. Infectious Diseases Designer proteins produce potent HIV defense Jon Cohen AIDS vaccine developers mimic natural route to powerful immune responses. U.S. Research Funding Republicans split on climate, social science spending Jeffrey Mervis House calls for cuts, Senate favors status quo. Geoscience Pumped up to rumble Julia Rosen Massive studies of wastewater injection wells show fast pumping raises earthquake risk. Feature Last dance? Marianne Lavelle An urgent effort to save the West’s iconic lesser prairie chicken could point the way to a truce in other endangered-species battles. Sage grouse war tests limits of partnership in West Marianne Lavelle The prairie chicken could provide a blueprint for settling the sage grouse war. Working Life Do it for love Marek Wagner Letters Germline gene therapy: We’re ready Henry I. Miller Research ethics and health care reform James G. Kahn and Paul Hofmann Spitzer’s stellar work M. W. Werner et al. Books et al. Summer Reading Summer books for the science-minded Tasty Pina Fritz Invisible Sean P. Rodrigues The Last Unicorn David W. Redding The Age of Cryptocurrency Marie Vasek On the Move Benjamin Combs Seveneves Daniel Tamayo Rain Rachel McCrary A Buzz in the Meadow Michelle Duennes Books Received A listing of books received at Science during the week ending 12 June 2015. Policy Forum Nuclear Security After the Iran deal: Multinational enrichment Alexander Glaser et al. World powers should buy a stake in Iran’s enrichment capacity and accept the same rules ADVERTISEMENT Perspectives Conservation When the hunter becomes the hunted Rosie Woodroffe and Stephen M. Redpath Effective predator management relies on social acceptability as well as scientific evidence Cell Biology An ESCRT to seal the envelope Wesley I. Sundquist and Katharine S. Ullman Cellular machinery that remodels different lipid bilayers also closes the nuclear membrane Developmental Biology It’s about time for neural crest Stefan Hoppler and Grant N. Wheeler The unusual pluripotency of neural crest cells is inherited from embryonic stem cells [Also see Research Article by Buitrago-Delgado et al.] Membranes Outperforming nature’s membranes Viatcheslav Freger Ultrathin synthetic membranes that reach a record permeability can clean up organic solutions [Also see Report by Karan et al.] Water Conservation Are you watering your lawn? Terri S. Hogue and Stephanie Pincetl High-resolution data may help to devise effective water conservation strategies in urban areas around the world Immunology A Chlamydia vaccine on the horizon Robert C. Brunham Results of a new Chlamydia vaccine in mice should spur human clinical trials [Also see Research Article by Stary et al.] Retrospective John Forbes Nash Jr. (1928–2015) Martin Shubik A distinguished mathematician and Nobel laureate dies tragically Reviews Observing the Atlantic Meridional Overturning Circulation yields a decade of inevitable surprises M. A. Srokosz and H. L. Bryden Research Articles Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells Elsy Buitrago-Delgado et al. Neural crest cells may retain an embryonic expression program rather than reinventing it later. [Also see Perspective by Hoppler and Wheeler] A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells Georg Stary et al. A nanoparticle-based vaccine protects mice against infection with Chlamydia trachomatis. [Also see Perspective by Brunham] Reports High-rate injection is associated with the increase in U.S. mid-continent seismicity M. Weingarten et al. High injection rates of wastewater into deep wells increase the risk of earthquakes in regions prone to induced seismicity. Long-lived photoinduced polaron formation in conjugated polyelectrolyte-fullerene assemblies Rachel C. Huber et al. An aqueous micelle can stabilize separated charges created by photoinduced electron transfer for several days. Topological defect dynamics in operando battery nanoparticles A. Ulvestad et al. Coherent x-rays image structural transformations in battery nanoparticles during electrochemical operation. Sub–10 nm polyamide nanofilms with ultrafast solvent transport for molecular separation Santanu Karan et al. Thin, crumpled polymer films on ceramic supports are high-flux membranes for removing small molecules from organic fluids. [Also see Perspective by Freger] Cortical information flow during flexible sensorimotor decisions Markus Siegel et al. A dynamic network of cortical areas processing similar information but to different degrees is explored. The shape and structure of cometary nuclei as a result of low-velocity accretion M. Jutzi and E. Asphaug Three-dimensional simulations show that structures observed on cometary nuclei formed very early on by collisional coagulation. Shared decision-making drives collective movement in wild baboons Ariana Strandburg-Peshkin et al. Democracy guides group decisions in baboons, even in the presence of strong social hierarchies. Structural basis for nucleotide exchange in heterotrimeric G proteins Ron O. Dror et al. Atomic-level simulations show how G protein–coupled receptors trigger G protein signaling. Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces Shane Gonen et al. A computational approach allows the design of proteins that self-assemble into two-dimensional lattices. Endocytic sites mature by continuous bending and remodeling of the clathrin coat Ori Avinoam et al. The clathrin lattice appears to be remodeled during coated vesicle budding. Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4 H.‐T. Hsu et al. A transcription factor involved in cell-fate changes also facilitates chromatin opening. Phthalimide conjugation as a strategy for in vivo target protein degradation Georg E. Winter et al. A chemical strategy that leads to selective destruction of proteins of interest may be a valuable tool for drug development. Technical Comments Comment on “Early Homo at 2.8 Ma from Ledi-Geraru, Afar, Ethiopia” John Hawks et al. Comment on “Missing gas-phase source of HONO inferred from Zeppelin measurements in the troposphere” Chunxiang Ye et al. Response to Comment on “Early Homo at 2.8 Ma from Ledi-Geraru, Afar, Ethiopia” Brian Villmoare et al. Response to Comment on “Missing gas-phase source of HONO inferred from Zeppelin measurements in the troposphere” Xin Li et al. Podcast Science Podcast: 19 June Show On this week’s show: Using genetics to catch elephant poachers, the trouble with the letter R, and a roundup of daily news stories. New Products New Products A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers. From the AAAS Office of Publishing and Member Services Science Webinar Series Sourcing niche cell populations: Techniques for isolating and characterizing progenitor cells Donald G. Phinney and Stefano Da Sacco     About the Cover Also Online: Science Express Daily News Science Careers Science Signaling Science Translational Medicine Recommend to Your Library Podcast Listen now. Latest News DNA from elephant tusks reveals poaching routes Silver hairs keep desert ants cool Signs of democracy seen in typically authoritarian baboon society Feature: Researchers push to prevent a last dance for the lesser prairie chicken Feature: Sage grouse war tests limits of partnership in West ADVERTISEMENT Sponsored by Science & SciLifeLab Prize for Young Scientists    Want to be published in Science?    Want to receive US$30,000 for your research?    Now accepting entries    Science & SciLifeLab Prize for Young Scientists    Deadline: August 1, 2015    Visit www.sciencemag.org/scilifelabprize

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Science Express Notification for 19 June 2015

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Science/AAAS Webinar New technologies for translational research: Applying high-content screening in cancer research and personalized medicine Learn how high content screening and novel computer modeling are being applied to systems biology, translational cancer research, and personalized medicine. Register to view TODAY: webinar.sciencemag.org Produced by the Science/AAAS Custom Publishing Office and sponsored by PerkinElmer. Science Science Express   06/19/15 Volume 348, Issue 6241 New Science Express articles have been made available: Perspectives CONSERVATION Can DNA foil the poachers? By A. Rus Hoelzel Research Articles A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation Anand Minajigi et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Rogier W. Sanders et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen Joseph G. Jardine et al. Reports CONSERVATION Genetic assignment of large seizures of elephant ivory reveals Africa’s major poaching hotspots S. K. Wasser et al. Keeping cool: Enhanced optical reflection and heat dissipation in silver ants Norman Nan Shi et al. Science/AAAS Webinar New technologies for translational research: Applying high-content screening in cancer research and personalized medicine Learn how high content screening and novel computer modeling are being applied to systems biology, translational cancer research, and personalized medicine. Register to view TODAY: webinar.sciencemag.org Produced by the Science/AAAS Custom Publishing Office and sponsored by PerkinElmer.

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Science Latest News

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Latest News and Headlines 17 June 2015

Were rapidly depleting our supplies of groundwater

Weighing a hot Mars

Deep-sea sharks show surprising buoyancy

Astronomers spot first-generation stars, made from big bang

Guinea pig feasts may explain high rates of deadly parasite in Peru

Tasmanian devils create landscape of fear

Opossums caught acting surprisingly social

Earth’s core is brimming with brimstone

House bill would give NIH $1.1 billion more in 2016

DDT may quadruple breast cancer risk

Pope doesnt shy away from specifics in leaked climate encyclical

Energy harnessed from humidity can power small devices

How a scientist lost $3 million on TV’s Shark Tank—and still came out ahead

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Latest from Science News: Dinosaurs may not have seen the Grand Canyon after all

Latest from Science News 06/18/2015 View in browser Become a Subscribing Member» Science Ticker Dinosaurs may not have seen the Grand Canyon after all BY Anonymous, Jun 18, 2015 06:00 am New geologic comparisons peg the Grand Canyon’s inception well after dinosaurs went extinct. Read More Read More» Science Ticker Unpredictable egg scramble throws off parasitic parents BY Ashley Yeager, Jun 17, 2015 07:35 pm Eggs of some species of warbler and weaver birds appear to have individual signatures, which can help distinguish them from the eggs of parasitic cuckoos. Read More Read More» News in Brief How mantis shrimps spar BY Susan Milius, Jun 17, 2015 03:24 pm In ritualized combat between deadly mantis shrimp, blows count but don’t kill. Read More Read More» More Headlines from Science News Science Stats Most of Earth’s impact craters await discovery Hundreds of undiscovered impact craters probably dot Earth’s surface, new research estimates. Read More By Thomas Sumner, Jun 17, 2015 10:00 am Editor's Note Pluto at last Precision matters, whether looking at global temperatures, subatomic particles or the carefully timed approach to a faraway world. Read More By Eva Emerson, Jun 17, 2015 08:39 am Letters to the Editor Water's origin story, science and sci-fi and more reader feedback Readers discuss how Earth got its water, chat about a hot spot’s violent past and more. Read More By Science News Staff, Jun 17, 2015 08:39 am Feature Rehab for psychopaths Psychopaths often don’t fit movie stereotypes, but they share particular characteristics. New research shows that, contrary to popular thought, cognitive behavioral therapy can help some psychopaths stay out of prison. Read More By Bruce Bower, Jun 17, 2015 07:30 am News Distant galaxy may contain primeval stars A stockpile of the first generation of stars might be lighting up gas in a galaxy that existed roughly 800 million years after the Big Bang. Read More By Christopher Crockett, Jun 17, 2015 06:00 am Wild Things With Tasmanian devils gone, possums come down from the trees In areas where Tasmanian devils have largely disappeared, their prey is becoming more adventuresome, a new study finds. Read More By Sarah Zielinski, Jun 16, 2015 07:05 pm Science Ticker Homunculus reimagined A new study pinpoints the part of the brain that controls the neck muscles, tweaking the motor homunculus. Read More By Laura Sanders, Jun 16, 2015 05:16 pm Privacy Policy | Update Email Preferences | Unsubscribe from All SSP Newsletters | Contact Us Facebook | Twitter | Vimeo | Google+ Society for Science & the Public • 1719 N Street, N.W. Washington, DC 20036 • Copyright © 2015

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Sci Transl Med Table of Contents for 17 June 2015; Vol. 7, No. 292

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Sponsored by Association for Research in Vision and Ophthalmology Science Translational Medicine Table of Contents   06/17/15 Volume 7, Issue 292 <!––> Congratulations to Nicholas Navin from MD Anderson Cancer Center on winning the 2015 AAAS Martin and Rose Wachtel Cancer Research Award, and to the runners up, Agnel Sfeir (NYU) and Nitzan Rosenfeld (Cambridge). Did you miss…? Review: Immunotherapy for solid organ and HSC transplantation. <!– Last chance to register for Bridging Biomedical Worlds “From Neural Circuitry to Neurotechnology” in Tokyo. –> <!– Science Translational Medicine welcomes our 2015 Associate Scientific Advisors. –> <!– The focus of this week’s issue is cancer to coincide with the AACR annual meeting –> In this week’s issue: Research Articles BRAIN IMAGING Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomography Carmen Kut et al. Optical coherence tomography (OCT) can distinguish cancer from noncancer tissue in vivo in rodent models of human brain cancer and ex vivo in fresh human brain cancer specimens with high sensitivity and specificity. AUTOIMMUNITY Transglutaminase 4 as a prostate autoantigen in male subfertility Nils Landegren et al. TGM4 is a male-specific autoantigen for prostatitis associated with autoimmune polyendocrine syndrome type 1. TYPE DIABETES Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity Suneng Fu et al. New assays that measure endoplasmic reticulum (ER) function and protein folding identify a small molecule, azoramide, that exerts antidiabetic effects. CARDIOVASCULAR AGING Vinculin network–mediated cytoskeletal remodeling regulates contractile function in the aging heart Gaurav Kaushik et al. Cardiac vinculin overexpression is a conserved aging response that is associated with enhanced myocardial performance and extended organismal life span. Focus CARDIOVASCULAR AGING Cardiac aging: Send in the vinculin reinforcements Kristine Y. DeLeon-Pennell and Merry L. Lindsey Integration of multiple analytical approaches across three species—fly, rat, and nonhuman primate—reveals additional roles for vinculin in cytoskeletal aging and cardiovascular disease (Kaushik et al., this issue). Editors’ Choice CANCER When instability is a good thing Roxana Dronca Mismatch repair–deficient tumors have a high rate of somatic mutations, have higher neoantigen formation, and are more sensitive to immune checkpoint blockade. Cardiovascular Disease Monitoring blood pressure with your bathroom scale Thomas Heldt Imperceptible motions of the body can be measured with ballistocardiography and could help track cardiovascular variables and disease. CANCER MIF: A harbinger of evil Gadi Lalazar Macrophage migration inhibitory factor in pancreatic cancer exosomes initiates a premetastatic niche in the liver.     About the cover Also Online: Current Issue Information for Authors My Science Translational Medicine Recommend to Your Library Sponsored by Association for Research in Vision and Ophthalmology

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Harnessing energy from humidity, DDT increases cancer risk, & more

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Latest News and Headlines 16 June 2015

House bill would give NIH $1.1 billion more in 2016

DDT may quadruple breast cancer risk

Pope doesnt shy away from specifics in leaked climate encyclical

Energy harnessed from humidity can power small devices

How a scientist lost $3 million on TV’s Shark Tank—and still came out ahead

Climate report introduces sobriety to Paris talks

University of Minnesota to overhaul research protections

Congressional Republicans split over climate, social science spending

Raging fires, high temps kept big dinosaurs out of North America for millions of years

When a forest is burned, what comes back may not resemble what was lost

Scientists celebrate comet lander Philae’s call after 7-month slumber

MERS outbreak in Korea may be past its peak, panel says

U.S. move to regulate greenhouse emissions from aviation puts international rules on the runway

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Science Signaling Table of Contents for 16 June 2015; Volume 8, Issue 381

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Sponsored by Diagenode New! Transcription factor ChIP-seq with complete ease iDeal ChIP-seq Kit for Transcription Factors Start-to-finish ChIP including control antibodies such as CTCF and primers. Tackles the toughest transcription factor ChIPs and validated with multiple TFs including HDAC1, LSD1, p53, P300, HDAC2, EZH2, and many more. Learn more. Science Signaling Table of Contents   06/16/15 Volume 8, Issue 381 <!––> Special edition ebooks from Science Signaling on the topics of Cancer, Physiology, and Neuroscience: Download your copy! <!– –> In this week’s issue: Research Articles Cancer Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation Shanmugam Panneer Selvam et al. Sphingosine 1-phosphate binds and stabilizes telomerase, a process that could be targeted to promote senescence and reduce cancer growth. Cytokine Signaling Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation Qiong Xue et al. Comparing isolated cells with cell populations uncovers the contributions of autocrine and paracrine signaling to the secretion of cytokines by macrophages. Inflammation Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles Mateja Manček-Keber et al. Extracellular vesicles from patients with rheumatoid arthritis stimulate inflammation in a TLR4-dependent manner. Editors’ Choice Host-Pathogen Interactions Evicting bacteria by exosome Wei Wong Bladder epithelial cells expel uropathogenic Escherichia coli in exosomes when these bacteria neutralize lysosomal pH. Cell Biology Gβ proteins as components of E3 ubiquitin ligases Sudhakaran Prabakaran The G protein β subunit functions as an adaptor subunit for an E3 ligase that ubiquitylates the G protein–coupled receptor kinase GRK2. Cell Biology Going nuclear for long life Nancy R. Gough CLK-1 in worms and COQ7 in humans function in both the mitochondria and nucleus. Immunology Lowering the bar for autoimmunity Angela Colmone Drug Delivery Nano keeps MK2 inhibitor intact and on target Megan L. Frisk Encapsulating a kinase inhibitor in a pH-sensitive nanoparticle may be a strategy to prevent intimal hyperplasia in vascular grafts. Cancer Hedgehog to the rescue Yevgeniya Nusinovich Activation of the Hedgehog pathway drives FLT3-mutated leukemia, and dual pathway inhibition effectively inhibits tumor growth. Tissue Repair A shot in the arm for damaged tissue Paula A. Kiberstis A compound that inhibits prostaglandin degradation enhances tissue regeneration in multiple organs in mice. Immunology Detecting Gram-negative bacteria Kristen L. Mueller Eukaryotic cells use the host protein TIFA to sense the monosaccharide HBP, derived from Gram-negative bacteria. Cell Biology How cells sense connected chromosomes L. Bryan Ray A sensor for the mitotic spindle assembly checkpoint is revealed. Physiology Receptor in the brain controls breathing L. Bryan Ray A G protein–coupled receptor in the brain controls respiration. About the cover Also Online: Current Issue Table of Contents Science Signaling Homepage My Science Signaling Information for Authors Recommend to Your Library Sponsored by Diagenode New! Transcription factor ChIP-seq with complete ease iDeal ChIP-seq Kit for Transcription Factors Start-to-finish ChIP including control antibodies such as CTCF and primers. Tackles the toughest transcription factor ChIPs and validated with multiple TFs including HDAC1, LSD1, p53, P300, HDAC2, EZH2, and many more. Learn more.

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Philae lander wakes up, why dinosaurs stayed out of N. America, & more

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Latest News and Headlines 15 June 2015

University of Minnesota to overhaul research protections

Congressional Republicans split over climate, social science spending

Raging fires, high temps kept big dinosaurs out of North America for millions of years

When a forest is burned, what comes back may not resemble what was lost

Scientists celebrate comet lander Philae’s call after 7-month slumber

MERS outbreak in Korea may be past its peak, panel says

U.S. move to regulate greenhouse emissions from aviation puts international rules on the runway

In basketball, physics predicts how big a lead your team needs to win

Top stories: Drunk chimps, dinosaur blood, and irreproducible research

Blazing hot exoplanet has sunscreen layer

Research chimps to be listed as endangered

The scientist behind the personhood chimps

Senate Republicans threaten to block confirmation of EPA research chief

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Latest from Science News: Pneumonia bacteria attacks lungs with toxic weaponry

Latest from Science News 06/16/2015 View in browser Become a Subscribing Member» Science Ticker Pneumonia bacteria attacks lungs with toxic weaponry BY Helen Thompson, Jun 15, 2015 05:46 pm Some strains of the bacteria that causes pneumonia splash lung cells with hydrogen peroxide to mess with DNA and kill cells, a new study suggests. Read More Read More» News Alzheimer’s spares brain’s music regions BY Laura Sanders, Jun 15, 2015 08:00 am Brain regions involved in recognizing familiar songs are relatively unscathed in Alzheimer’s disease. Read More Read More» Science Ticker Comet lander Philae phones home BY Ashley Yeager, Jun 14, 2015 09:45 am The European Space Agency has received signals for its comet lander Philae, which touched down on comet 67P/Churyumov-Gerasimenko in November and has been in hibernation since. Read More Read More» More Headlines from Science News News Aging: Nature’s way of reducing competition for resources Aging may have developed in many species as a genetic mechanism to conserve future resources. If the controversial proposal is true, then scientists may be able to greatly extend life span by deactivating the machinery for aging embedded in our DNA. Read More By Andrew Grant, Jun 12, 2015 04:50 pm Wild Things Could the dinos of ‘Jurassic World’ become invasive? Even if they escaped their island home, the giant reptiles of ‘Jurassic World’ probably wouldn’t survive on the mainland. But the movie’s plants are another story. Read More By Sarah Zielinski, Jun 12, 2015 02:45 pm News A circadian clock transplant gives E. coli rhythm Clockworks from algae built into E. coli may hold future jet lag treatment. Read More By Tina Hesman Saey, Jun 12, 2015 02:11 pm Feature Rendezvous with Pluto Earth will get its first good look at Pluto and its five known moons when New Horizons sails past on July 14. Read More By Christopher Crockett, Jun 12, 2015 11:55 am Growth Curve Unlike moms, dads tend not to coo in squeaky voices American English-speaking moms dial up their pitch drastically when talking to their children, but dads’ voices tend to stay steady, a new study finds. Read More By Meghan Rosen, Jun 12, 2015 08:55 am News Fluid injection triggers earthquakes indirectly, study finds An up-close look at artificially triggered quakes suggests that tremors start slow and smooth. Read More By Thomas Sumner, Jun 11, 2015 02:00 pm News A protein variant can provide protection from deadly brain-wasting If cannibalism hadn’t stopped, a protective protein may have ended kuru anyway. Read More By Tina Hesman Saey, Jun 11, 2015 01:34 pm Privacy Policy | Update Email Preferences | Unsubscribe from All SSP Newsletters | Contact Us Facebook | Twitter | Vimeo | Google+ Society for Science & the Public • 1719 N Street, N.W. Washington, DC 20036 • Copyright © 2015

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