Table of Contents for 12 June 2015; Vol. 348, No. 6240

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Science/AAAS Science

Table of Contents
 

06/12/15 Volume 348, Issue 6240

In this week’s issue:


Research Summaries

Editor summaries of this week’s papers.

Highlights of the recent literature.


Editorial


In Brief

A roundup of weekly science policy and related news.


In Depth

Infectious Diseases

South Korea’s explosive outbreak gives scientists fresh opportunities to study the virus.

Paleontology

Can soft tissue survive 75 million years?

Paleoclimatology

Ancient lake sediments in China record epic temperature swings, biotic turnover before the mass extinction.

Neuroscience

NIH workshop delves into challenges of testing invasive neuromodulation technology.

Animal Rights

Susan Larson defends her work with two research chimpanzees at the heart of a legal battle.

Molecular Epidemiology

New studies could aid public health efforts.


Feature

What does it take for an academic scientist to become an entrepreneur? Here are some of their stories.

Two venture capitalists explain the investor’s mindset.

Biotech incubators such as LabCentral are lowering barriers to entrepreneurship.


Working Life


Letters


Books et al.

History of Science

A commitment to national self-sufficiency set the stage for the rise of India’s information technology industry

Agricultural Science

It’s time to talk about the future of food

A listing of books received at Science during the week ending 05 June 2015.


Policy Forum

Entrepreneurship

Entrepreneurship

Entrepreneurship

Entrepreneurship

Entrepreneurship

Entrepreneurship

Entrepreneurship
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Perspectives

Seismology

Controlling fluid injection may mitigate the extent of induced earthquakes [Also see Report by Guglielmi et al.]

Genetics

Isolation of lagging chromosomes in micronuclei causes catastrophic genome rearrangements

Immunology

Bacteria can activate innate immune responses by releasing a metabolite that enters host cells [Also see Report by Gaudet et al.]

Biomedicine

A small molecule that prevents the breakdown of a prostaglandin promotes tissue regeneration [Also see Research Article by Zhang et al.]

Atmospheric Science

Changes in atmospheric pressure may be an important long-term climate forcing mechanism [Also see Report by Poulsen et al.]

Nanomaterials

A new precursor library yields high-quality quantum dots for device applications [Also see Report by Hendricks et al.]

Organismal Biology

Even in dim light, hawkmoths can track the motions of wind-tossed flowers [Also see Report by Sponberg et al.]


Reviews


Research Articles

A compound that inhibits prostaglandin degradation enhances tissue regeneration in multiple organs in mice. [Also see Perspective by FitzGerald]


Reports

Real-time observations of a reactivated fault provide an option for monitoring of earthquake-inducing wastewater injection. [Also see Perspective by Cornet]

High-quality quantum dots with tunable particle size and composition are fabricated using inexpensive thioureas. [Also see Perspective by Hens]

Molybdenum-doped platinum-nickel nanocrystal catalysts exhibit high activity and durability for a key fuel cell reaction.

An intramolecular exchange process enables growth of high-quality organic perovskite films with greater solar spectral range.

Atmospheric oxygen concentrations may have had an important indirect effect on climate in the distant past. [Also see Perspective by Peppe and Royer]

Gene expression is more similar than expected by chance in brain regions that are functionally connected.

Moth vision in low light matches that needed to follow swaying flowers. [Also see Perspective by Warrant]

Human-mediated dispersal of mollusks is changing the way they can colonize new environments.

Eukaryotic cells use the host protein TIFA to sense the monosaccharide HBP, derived from Gram-negative bacteria. [Also see Perspective by Brubaker and Monack]

A G protein–coupled receptor in the brain controls respiration.

A sensor for the mitotic spindle assembly checkpoint is revealed.

A sensor for the mitotic spindle assembly checkpoint is revealed.

An M-locus gene is necessary and sufficient for male development in the mosquito that transmits dengue and yellow fever.


Technical Comments


Podcast

On this week’s show: Tracking aquatic animals, cochlear implants and emotion recognition, and a roundup of daily news stories.


New Products

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.


From the AAAS Office of Publishing and Member Services

Business Office Feature

 
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Improving Tissue-Sample Profiling: The Optimization and Application of Immunohistochemistry
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Understanding the basic principles underlying IHC and how to address the technical aspects of experimental design are key to producing high-quality, reproducible data. In this webinar, we will hear from experts who will share their insights into assay design.
Register TODAY: webinar.sciencemag.org
Produced by the Science/AAAS Custom Publishing Office and sponsored by EMD Millipore.

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Science Express Notification for 12 June 2015

Sponsored by Eppendorf & Science Prize for Neurobiology

   Eppendorf & Science Prize for Neurobiology
   Now accepting entries for the US$25,000
   Deadline: June 15, 2015


Science/AAAS Science

Science Express
 

06/12/15 Volume 348, Issue 6240

New Science Express articles have been made available:


Research Articles

MAGNETISM


Reports


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The birth of the Bronze Age, the biggest ring in the solar system, & more

 

Latest News and Headlines

10 June 2015

 

 

 

In wake of court defeat, opponents of Obama’s climate rule tee up seven more attacks
 

 
 

 

 

Marine scientists discover 100 new species in Filipino Easter egg hunt
 

 
 

 

 

Scientists call on Canada to bar new oil sands development
 

 
 

 

 

Nomadic herders left a strong genetic mark on Europeans and Asians
 

 
 

 

 

The biggest planetary ring in the solar system
 

 
 

 

 

Nuclear blasts shed light on how animals recover from annihilation
 

 
 

 

 

Journals investigate climate skeptic author’s ties to fossil fuel firm as new allegations arise
 

 
 

 

 

World’s heaviest dinosaur just lost tons of weight
 

 
 

 

 

Chimps caught drinking after hours
 

 
 

 

 

For HPV vaccine, one dose goes a long way
 

 
 

 

 

Study claims $28 billion a year spent on irreproducible biomedical research
 

 
 

 

 

Record U.S. rains trigger wildfire fears. How’s that work?
 

 
 

 

 

NSF research program for have-not states faces growing criticism
 

 
 

 

 


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Latest from Science News: Human laugh lines traced back to ape ancestors

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06/11/2015

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Human laugh lines traced back to ape ancestors

BY Bruce Bower,

Chimps make laughing faces that speak to evolution of human ha-ha’s. Read More

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WISE satellite measures girth of Saturn’s widest ring

BY Christopher Crockett,

Saturn’s dark, outermost ring is about 270 times as wide as the planet itself. Read More

News in Brief

Some of sun’s magnetic fields may act more like forests

BY Christopher Crockett,

A swaying forest of mangrovelike magnetic fields on the sun could be the answer to why the solar atmosphere is millions of degrees hotter than the surface. Read More

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Sci Transl Med Table of Contents for 10 June 2015; Vol. 7, No. 291

Sponsored by Pall Corporation


Science/AAAS Science Translational Medicine

Table of Contents
 

06/10/15 Volume 7, Issue 291


<!–GTC–>

Congratulations to Nicholas Navin from MD Anderson Cancer Center on winning the 2015 AAAS Martin and Rose Wachtel Cancer Research Award, and to the runners up, Agnel Sfeir (NYU) and Nitzan Rosenfeld (Cambridge).

DMM

Did you miss…? Review: Immunotherapy for solid organ and HSC transplantation.

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Last chance to register for Bridging Biomedical Worlds “From Neural Circuitry to Neurotechnology” in Tokyo.

–> <!–EC

Science Translational Medicine welcomes our 2015 Associate Scientific Advisors.

–> <!–Cancer

The focus of this week’s issue is cancer to coincide with the AACR annual meeting

–>

In this week’s issue:


Research Articles

MULTIPLE SCLEROSIS

Genetic variants associated with multiple sclerosis result in increased NFκB signaling in CD4 T cells and a decreased threshold for activation.

BIOENGINEERING

Nanoparticle-functionalized T cells actively transport a cytotoxic drug to systemic sites of lymphoma dissemination, enhancing the efficacy of antitumor chemotherapy.

NANOMEDICINE

Nanopolyplexes formulated from a pH-responsive, endosomolytic polymer with a peptide inhibitor of MAPKAP kinase 2 block inflammatory and migratory signaling in vascular smooth muscle cells and prevent intimal hyperplasia in human saphenous vein grafts.

CANCER

Activation of the Hedgehog pathway drives FLT3-mutated leukemia, and dual pathway inhibition effectively inhibits tumor growth.

HUMAN GENETICS

Basal exon skipping, a mechanism by which a cell compensates for deleterious mutations, explains pleiotropic disease pathogenesis in patients with mutations in two different ciliopathy-associated genes.


Focus

CELL THERAPY

The homing capacity of T cells was used to deliver drug-laden nanoparticles to lymphoma cells resident in lymph nodes.

HUMAN GENETICS

The total amount of functional mutant protein produced by cells underpins disease pleiotropy in the ciliopathies.

POLICY

The premier position of medical research on the U.S. national policy agenda marks a pivotal point in the evolution of patient engagement.


Editors’ Choice

PULMONARY DISEASE

Carbon and wood smoke particulates impair alveolar macrophage-mediated immunity and increase the risk for pulmonary infection.

SLEEP AND MEMORY

β-Amyloid pathology may impair memory function in Alzheimer’s disease and aging by decreasing slow wave activity during sleep.

IMMUNOTHERAPY

A chemical screen highlights a new pathway controlling regulatory T cell differentiation.

FIBROSIS

Perivascular adipocyte progenitors can be tipped to fibrose by growth factor signaling in white adipose tissues.

EPIGENETICS

Prenatal exposure to famine has a critical time period for DNA-methylation alterations in blood cells later in life.

 
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Dinosaur tissue discovered, irreproducible research, & more

 

Latest News and Headlines

9 June 2015

 

 

 

Study claims $28 billion a year spent on irreproducible biomedical research
 

 
 

 

 

Record U.S. rains trigger wildfire fears. How’s that work?
 

 
 

 

 

NSF research program for have-not states faces growing criticism
 

 
 

 

 

Signs of ancient cells and proteins found in dinosaur fossils
 

 
 

 

 

Eight hundred fourteen ghostly galaxies found in famous cluster
 

 
 

 

 

Russian researchers protest government reforms
 

 
 

 

 

Astronomers find 11.6-billion-year-old star nursery in ancient galaxy
 

 
 

 

 

Why some stars are born alone
 

 
 

 

 

Contamination scare at NIH leaves clinical trial subjects with tough choice
 

 
 

 

 

Chinese-American physicist pleads not guilty to technology theft
 

 
 

 

 

Did poor ventilation lead to MERS superspread in Korea?
 

 
 

 

 

Top stories: Hellboy the dinosaur, why humans are the fat primate, and great news for hypochondriacs
 

 
 

 

 

Maya ancestry may help explain the high risk of diabetes in Mexico
 

 
 

 

 


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Dinosaur tissue discovered, irreproducible research, & more

 

Latest News and Headlines

9 June 2015

 

 

 

Study claims $28 billion a year spent on irreproducible biomedical research
 

 
 

 

 

Record U.S. rains trigger wildfire fears. How’s that work?
 

 
 

 

 

NSF research program for have-not states faces growing criticism
 

 
 

 

 

Signs of ancient cells and proteins found in dinosaur fossils
 

 
 

 

 

Eight hundred fourteen ghostly galaxies found in famous cluster
 

 
 

 

 

Russian researchers protest government reforms
 

 
 

 

 

Astronomers find 11.6-billion-year-old star nursery in ancient galaxy
 

 
 

 

 

Why some stars are born alone
 

 
 

 

 

Contamination scare at NIH leaves clinical trial subjects with tough choice
 

 
 

 

 

Chinese-American physicist pleads not guilty to technology theft
 

 
 

 

 

Did poor ventilation lead to MERS superspread in Korea?
 

 
 

 

 

Top stories: Hellboy the dinosaur, why humans are the fat primate, and great news for hypochondriacs
 

 
 

 

 

Maya ancestry may help explain the high risk of diabetes in Mexico
 

 
 

 

 


Dog
 

 
 

 

   

 

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Science Signaling Table of Contents for 09 June 2015; Volume 8, Issue 380

Sponsored by Cell Signaling Technology, Inc.

Science/AAAS Science Signaling

Table of Contents
 

06/09/15 Volume 8, Issue 380


<!–ebooks–> Special edition ebooks from Science Signaling on the topics of Cancer, Physiology, and Neuroscience: Download your copy! <!–
–>

In this week’s issue:


Focus

Microbiology

Arginine may trigger biofilm formation by a human pathogen by stimulating c-di-GMP production.


Research Articles

Posttranslational Modifications

A chemotherapeutic triggers the degradation of an oncoprotein by inducing a switch from SUMO2 to SUMO1 at a specific lysine residue.

Microbiology

The human pathogen Salmonella senses ʟ-arginine and responds by increasing c-di-GMP and cellulose synthesis.


Research Resources

Phosphoproteomics

A mass spectrometry method may enable the simultaneous and rapid quantification of multiple phosphorylation events in multiple samples.


Podcasts

Posttranslational Modifications

Arsenic trioxide treatment switches which SUMO variant is conjugated to an oncoprotein, thus triggering its degradation.


Editors’ Choice

Cancer

Pancreatic tumors release exosomes that prime the liver for metastasis.

Cancer

Lysyl oxidase secreted by primary tumors promotes the formation of a niche for bone metastases.

Developmental Biology

Mass spectrometry analysis of metabolites reveals functional differences in individual cells in the early developing embryo.

Cell Migration

Cysteine oxidation inhibits cofilin activity in the leading edge of migrating cells.

Pregnancy

Reduction of vascular RGS5 causes hypertension and preeclampsia, which can be reversed by PPAR agonist treatment in mouse models.

Regeneration

The capacity for regeneration can be elicited in adult mice by drug-induced stabilization of HIF-1α (hypoxia-inducible factor 1α).

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An 11.6-billion-year-old star nursery, ghostly galaxies, & more

 

Latest News and Headlines

8 June 2015

 

 

 

Eight hundred fourteen ghostly galaxies found in famous cluster
 

 
 

 

 

Russian researchers protest government reforms
 

 
 

 

 

Astronomers find 11.6-billion-year-old star nursery in ancient galaxy
 

 
 

 

 

Why some stars are born alone
 

 
 

 

 

Contamination scare at NIH leaves clinical trial subjects with tough choice
 

 
 

 

 

Chinese-American physicist pleads not guilty to technology theft
 

 
 

 

 

Did poor ventilation lead to MERS superspread in Korea?
 

 
 

 

 

Top stories: Hellboy the dinosaur, why humans are the fat primate, and great news for hypochondriacs
 

 
 

 

 

Maya ancestry may help explain the high risk of diabetes in Mexico
 

 
 

 

 

Galaxy collisions cause starbursts
 

 
 

 

 

European Space Agency picks finalists for next science mission
 

 
 

 

 

MERS Virus
 

 
 

 

 

Podcast: Finicky cats, cancer-detecting bacteria, and more
 

 
 

 

 


Dog
 

 
 

 

   

 

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Latest from Science News: MERS virus didn’t morph in its move to South Korea

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06/09/2015

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MERS virus didn’t morph in its move to South Korea

BY Tina Hesman Saey,

No obvious changes in the MERS virus account for its rapid spread in South Korea. Read More

News

Tracing molecules’ movement in nails may help fight fungus

BY Sarah Schwartz,

Tracking chemicals through the human nail may provide valuable insight for drug development. Read More

Science Stats

Greenhouse effect from fossil fuels felt almost immediately

BY Thomas Sumner,

The warming caused by burning fossil fuels is surpassed within months by the greenhouse gas effect of the released carbon dioxide, new research shows. Read More

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