Science Express Notification for 10 July 2015

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Sponsored by Immunogenomics 2015 HudsonAlpha Institute presents Immunogenomics 2015! An international conference that brings together leaders and researchers exploring the application of genomics technologies to understand the immune system and development of disease. September 29 – 30, 2015 Huntsville, Alabama, USA http://hudsonalpha.org/immunogenomicsconference/ Science Science Express   07/10/15 Volume 349, Issue 6244 New Science Express articles have been made available: Research Articles Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations Satoshi Okada et al. QUANTUM OPTICS Universal linear optics Jacques Carolan et al. Reports QUANTUM INFORMATION Coherent coupling between a ferromagnetic magnon and a superconducting qubit Yutaka Tabuchi et al. Recent hiatus caused by decadal shift in Indo-Pacific heating Veronica Nieves et al. ROCK PHYSICS Rock physics of fibrous rocks akin to Roman concrete explains uplifts at Campi Flegrei Caldera Tiziana Vanorio and Waruntorn Kanitpanyacharoen The microbiota regulates type 2 immunity through RORγt+ T cells Caspar Ohnmacht et al. Sponsored by Immunogenomics 2015 HudsonAlpha Institute presents Immunogenomics 2015! An international conference that brings together leaders and researchers exploring the application of genomics technologies to understand the immune system and development of disease. September 29 – 30, 2015 Huntsville, Alabama, USA http://hudsonalpha.org/immunogenomicsconference/

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Triceratops relative unearthed, spider sex, & more

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Latest News and Headlines 8 July 2015

Early relative of Triceratops unearthed

McNutt nomination for U.S. academy will benefit women, climate debate, researchers say

Pluto caps one scientists 50-year exploration of the solar system

Catastrophic Chinese floods triggered by air pollution

Nerves found in spider sex organ

Do 3D movies make us clumsy?

Updated: Southern California schools in legal clash over Alzheimer’s grant

Need an energy boost? This enzyme may help

Updated: Independent group pans WHOs response to Ebola

U.K. may send more people into space

Greek no vote leaves researchers in uncertainty

Astronomers offer vision of the next giant space telescope

Science Editor-in-Chief Marcia McNutt set to become first woman to lead U.S. National Academy of Sciences

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Latest from Science News: How dinos like Triceratops got their horns

Latest from Science News 07/09/2015 View in browser Become a Subscribing Member» Science Ticker How dinos like Triceratops got their horns BY Ashley Yeager, Jul 08, 2015 03:24 pm A new dino named Wendiceratops pinhornensis gives hints about how Triceratops and other relatives got their horns. Read More Read More» News Gene therapy restores hearing in mice BY Sarah Schwartz, Jul 08, 2015 02:00 pm Scientists have used gene therapy to restore hearing in deaf mice. Read More Read More» Wild Things Cuckoos may have a long-lasting impact on other birds BY Sarah Zielinski, Jul 08, 2015 01:02 pm Some birds that don’t have to worry about parasites like cuckoos reject eggs that aren’t their own. It might be a legacy of long-ago parasitism. Read More Read More» More Headlines from Science News News Age isn’t just a number Getting old happens faster for some, and the reason may be in the blood. Read More By Tina Hesman Saey, Jul 07, 2015 07:00 am Science Ticker New Horizons recovers from overload, is on track for Pluto flyby New Horizons transmits the best pictures of Pluto to date shortly before the spacecraft went quiet over the weekend. Read More By Christopher Crockett, Jul 06, 2015 05:49 pm News in Brief Beta Pictoris planet makes waves Spiral waves whip through the belt of debris around a young star — and it’s all a giant planet’s fault. Read More By Christopher Crockett, Jul 06, 2015 12:00 pm News Magnetic test boosts case for record-setting superconductor New measurements bolster the case that hydrogen sulfide is superconducting at about 200 kelvins, roughly 40 kelvins higher than any other known material. Read More By Andrew Grant, Jul 06, 2015 08:30 am How Bizarre Plastic shell lets roach-bot squeeze through gaps An arched shell helps a six-legged robot shimmy past obstacles. Read More By Meghan Rosen, Jul 06, 2015 07:00 am Wild Things Seabirds may navigate by scent Shearwaters may use olfactory cues to find islands far across the open ocean, a new study suggests. Read More By Sarah Zielinski, Jul 03, 2015 07:44 am Science Ticker Why seahorses have square tails 3-D printed seahorse tails reveal possible benefits of square cross-sections for armor and gripping. Read More By Susan Milius, Jul 02, 2015 02:34 pm Privacy Policy | Update Email Preferences | Unsubscribe from All SSP Newsletters | Contact Us Facebook | Twitter | Vimeo | Google+ Society for Science & the Public • 1719 N Street, N.W. Washington, DC 20036 • Copyright © 2015

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Sci Transl Med Table of Contents for 08 July 2015; Vol. 7, No. 295

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Sponsored by Immunogenomics 2015 HudsonAlpha Institute presents Immunogenomics 2015! An international conference that brings together leaders and researchers exploring the application of genomics technologies to understand the immune system and development of disease. September 29 – 30, 2015 Huntsville, Alabama, USA http://hudsonalpha.org/immunogenomicsconference/ Science Translational Medicine Table of Contents   07/08/15 Volume 7, Issue 295 <!––> <!– Congratulations to Nicholas Navin from MD Anderson Cancer Center on winning the 2015 AAAS Martin and Rose Wachtel Cancer Research Award, and to the runners up, Agnel Sfeir (NYU) and Nitzan Rosenfeld (Cambridge). –> Did you miss…? Perspective: Global implementation of genomic medicine Did you miss…? Commentary: Nourishing the translational research environment <!– Last chance to register for Bridging Biomedical Worlds “From Neural Circuitry to Neurotechnology” in Tokyo. –> <!– Science Translational Medicine welcomes our 2015 Associate Scientific Advisors. –> <!– The focus of this week’s issue is cancer to coincide with the AACR annual meeting –> In this week’s issue: Research Articles DEAFNESS Tmc gene therapy restores auditory function in deaf mice Charles Askew et al. Injection of AAV vectors that encoded wild-type Tmc1 or Tmc2 restores auditory function in mouse models of human deafnesses DFNB7/11 and DFNA36. LUNG DISEASE The proinflammatory role of HECTD2 in innate immunity and experimental lung injury Tiffany A. Coon et al. Antagonizing the E3 ligase HECTD2 reduces inflammation severity and experimental lung injury. Reports INFERTILITY Absence of sperm RNA elements correlates with idiopathic male infertility Meritxell Jodar et al. Absence of required RNA elements in sperm correlates with infertility but can be overcome with assisted reproductive technologies. Editorial ANTIBIOTIC RESISTANCE Stopping superbugs, maintaining the microbiota Victor Nizet The U.S. National Action Plan for Combating Antibiotic-Resistant Bacteria will succeed only if we alter the definition of “antibiotic.” Focus DEAFNESS Gene therapy for deafness: How close are we? Tobias Moser Virus-mediated transfer of genes encoding the mechanotransducer channel candidates TMC1 and TMC2 into hair cells of the ear partially restores hearing in animal models of human genetic deafness (Askew et al., this issue). Editors’ Choice METABOLISM Alcohol’s BOLD effect on food intake Jessica A. Alvarez The hypothalamus may mediate alcohol-induced munchies. CANCER Untangling the diversity of KRAS-driven lung adenocarcinoma Sam Behjati KRAS-driven lung adenocarcinomas can be organized into three subgroups with different phenotypes. GENE THERAPY Canavan disease: Can two wrongs make a right? Christopher G. Janson Double-knockout mice that lack both aspartoacylase (ASPA) and NAA synthase (Nat8L) show improved myelination and behavioral recovery, partially circumventing the effects of Canavan disease. FIBROSIS Battle scars: SAP and CRP Kara L. Spiller A subtle structural difference between closely related proteins determines their ability to promote or inhibit fibrosis. BIOMATERIALS Electronics, freshly squeezed Ian Y. Wong Flexible mesh nanosensors can be syringe-injected into the brain for multiplexed recording. Errata Erratum for the Research Article: “Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia” by Y. Lim, L. Gondek, L. Li, Q. Wang, H. Ma, E. Chang, D. L. Huso, S. Foerster, L. Marchionni, K. McGovern, D. N. Watkins, C. D. Peacock, M. Levis, B. D. Smith, A. A. Merchant, D. Small, W. Matsui     Also Online: Current Issue Archives About the Journal Information for Authors Recommend to Your Library Sponsored by Immunogenomics 2015 HudsonAlpha Institute presents Immunogenomics 2015! An international conference that brings together leaders and researchers exploring the application of genomics technologies to understand the immune system and development of disease. September 29 – 30, 2015 Huntsville, Alabama, USA http://hudsonalpha.org/immunogenomicsconference/

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An enzyme energy boost, Greek science uncertainty, & more

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Latest News and Headlines 7 July 2015

Updated: Southern California schools in legal clash over Alzheimer’s grant

Need an energy boost? This enzyme may help

Updated: Independent group pans WHOs response to Ebola

U.K. may send more people into space

Greek no vote leaves researchers in uncertainty

Astronomers offer vision of the next giant space telescope

Science Editor-in-Chief Marcia McNutt set to become first woman to lead U.S. National Academy of Sciences

Astronomers spot the pebbles that turn into planets

Geologist reflects on life behind bars in China

Hybrid animals like grolar bears not expected to be common consequence of climate change

Old-age protein may cause memory loss

European Commission tasks scouts to find suitable science advisers

Greek researchers worry as crucial referendum looms

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Science Signaling Table of Contents for 07 July 2015; Volume 8, Issue 384

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Sponsored by Diagenode The easiest NGS Library preparation you will ever use! The MicroPlex Library Preparation Kit offers A quick 3-step protocol without tube transfers Picogram inputs with high reprodicubility Perfect ChIP compatibility down to 10,000 cells. Superb multiplexing with 48 barcodes included Learn more Science Signaling Table of Contents   07/07/15 Volume 8, Issue 384 <!––> Meet the Science Signaling Editorial Team. <!– –> In this week’s issue: Research Articles Neurodegeneration Reelin protects against amyloid β toxicity in vivo Courtney Lane-Donovan et al. Reelin prevents the deleterious effects of amyloid β on synaptic transmission, learning, and memory. Posttranslational Modifications Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation Karthik Raju et al. Protein S-nitrosylation controls the brain’s use of glutamate for energy or neurotransmission. Research Resources Posttranslational Modifications Proteotoxic stress reprograms the chromatin landscape of SUMO modification Anne Seifert et al. Cells use SUMO-2 to stabilize chromatin-associated proteins and cope with stress. Reviews Cell Biology Function and dysfunction of two-pore channels Sandip Patel Channels on endosomal-lysosomal membranes are appealing targets for treatment of Parkinson’s disease and Ebola infection. Podcasts Neurodegeneration Science Signaling Podcast: 7 July 2015 Courtney Lane-Donovan et al. A secreted protein that controls synaptic plasticity protects neurons from the toxic effects of amyloid β. Editors’ Choice Neuroscience A pro-memory prion protein Leslie K. Ferrarelli Neuronal activity stimulates the deSUMOylation and aggregation of CPEB3, which promotes memory formation and maintenance. Immunology Constraining regulatory T cells John F. Foley A receptor for the lipid lysophosphatidylserine reduces regulatory T cell function during inflammation to promote immune responses. Neuroscience Sleep cyclin Annalisa M. VanHook The transcriptional cofactor Taranis promotes sleep by decreasing the abundance of CycA and inhibiting Cdk1. Biochemistry Clearing out selenoprotein garbage Guy Riddihough A surveillance system recognizes and degrades truncated proteins that fail to incorporate a specific amino acid. Cardiac Physiology Two hits in viral cardiomyopathy Megan Frisk Enterovirus-derived C-terminal dystrophin fragment is a dominant-negative peptide representing a new therapeutic target for viral cardiomyopathy remediation. Proteomics B cell receptor signaling dynamics Sudhakaran Prabakaran Quantitative mass spectrometry–based proteomics analysis reveals the phosphorylation and ubiquitylation dynamics of B cell receptor complexes. Also Online: Current Issue Archives About Science Signaling Information for Authors Recommend to Your Library Sponsored by Diagenode The easiest NGS Library preparation you will ever use! The MicroPlex Library Preparation Kit offers A quick 3-step protocol without tube transfers Picogram inputs with high reprodicubility Perfect ChIP compatibility down to 10,000 cells. Superb multiplexing with 48 barcodes included Learn more

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An old-age protein, how pebbles turn into stars, & more

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Latest News and Headlines 6 July 2015

Southern California schools clash in court over Alzheimer’s grant

Astronomers offer vision of the next giant space telescope

Science Editor-in-Chief Marcia McNutt set to become first woman to lead U.S. National Academy of Sciences

Astronomers spot the pebbles that turn into planets

Geologist reflects on life behind bars in China

Hybrid animals like grolar bears not expected to be common consequence of climate change

Old-age protein may cause memory loss

European Commission tasks scouts to find suitable science advisers

Greek researchers worry as crucial referendum looms

Podcast: The physics of groovy drumming, a bizarre bobcat burial, and more

QA: Biological oceanographer Mark Abbott to lead Woods Hole institute

Your brain is like a wad of paper

Feature: How what we eat is destroying our livers

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Latest from Science News: New Horizons recovers from overload, is on track for Pluto flyby

Latest from Science News 07/07/2015 View in browser Become a Subscribing Member» Science Ticker New Horizons recovers from overload, is on track for Pluto flyby BY Christopher Crockett, Jul 06, 2015 05:49 pm New Horizons transmits the best pictures of Pluto to date shortly before the spacecraft went quiet over the weekend. Read More Read More» News in Brief Beta Pictoris planet makes waves BY Christopher Crockett, Jul 06, 2015 12:00 pm Spiral waves whip through the belt of debris around a young star — and it’s all a giant planet’s fault. Read More Read More» How Bizarre Plastic shell lets roach-bot squeeze through gaps BY Meghan Rosen, Jul 06, 2015 07:00 am An arched shell helps a six-legged robot shimmy past obstacles. Read More Read More» More Headlines from Science News News Wrinkled brain mimics crumpled paper Brains crumple up just like wads of paper, a new study suggests. Read More By Laura Sanders, Jul 02, 2015 02:00 pm News Missing enzyme to blame for scentless roses The unusual enzyme behind roses’ sweet smell may help researchers revive the flower’s potent aroma. Read More By Beth Mole, Jul 02, 2015 02:00 pm Science Ticker Pluto may have spots the size of Missouri Dark spots emerge on the surface of Pluto in recent images from the New Horizons spacecraft. Read More By Christopher Crockett, Jul 02, 2015 12:10 pm News Smell test may detect autism A quick sniff test could reveal whether or not a child has autism, but some scientists have doubts. Read More By Meghan Rosen, Jul 02, 2015 12:00 pm Science Ticker Genetic tweak hints at why mammoths loved the cold An altered temperature sensor helped mammoths adapt to the cold. Read More By Tina Hesman Saey, Jul 02, 2015 12:00 pm Context Science is heroic, with a tragic (statistical) flaw Science falls short of its own standards because of the mindless use of ritualistic statistical tests. Read More By Tom Siegfried, Jul 02, 2015 11:29 am Introducing Centipede discovered in caves 1,000 meters belowground A newly discovered centipede species lives deep underground. Read More By Sarah Schwartz, Jul 02, 2015 10:44 am Privacy Policy | Update Email Preferences | Unsubscribe from All SSP Newsletters | Contact Us Facebook | Twitter | Vimeo | Google+ Society for Science & the Public • 1719 N Street, N.W. Washington, DC 20036 • Copyright © 2015

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Gene therapy for cystic fibrosis, medications sway moral judgement, & more

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News from Science Latest News   3 July 2015 Latest news and headlines from Science and ScienceInsider 03 July 2015 | Europe Greek researchers worry as crucial referendum looms Leaving the Eurozone could have devastating consequences for science 03 July 2015 | Scientific Community Podcast: The physics of groovy drumming, a bizarre bobcat burial, and more Listen to a roundup of some of our favorite stories from the week 02 July 2015 | Today’s secret to make you click this headline 02 July 2015 | People Events Q&A: Biological oceanographer Mark Abbott Abbott tapped to head Woods Hole Oceanographic Institution amid rough seas for ocean sciences 02 July 2015 | Astronomers are watching the birth of a planet 02 July 2015 | Biology Your brain is like a wad of paper Simple physics of crumpling explains elaborate folding of mammalian brains 02 July 2015 | Biology Feature: How what we eat is destroying our livers As obesity rates soar, a sometimes fatal liver disease is becoming epidemic 02 July 2015 | Warmer temperatures trigger sex change in wild reptiles 02 July 2015 | Tiny plankton has humanlike eye 02 July 2015 | Biology Common medications sway moral judgment Serotonin and dopamine drugs may change willingness to inflict harm on self and others 02 July 2015 | Archaeology Ancient bobcat buried like a human being Necklace-wearing kitten in Native American grave may shed light on animal domestication

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Editor’s picks: Quantum dots shine, e-cig dangers, latest from Pluto, what made plague deadly, science’s Achilles heel, & lizards and flatworms, oh my

Science News Editor’s Picks 07/05/15 View in browser Become a Subscribing Member » Feature Quantum dots get a second chance to shine By Alexandra Witze Quantum dots, semiconductor particles that can emit a rainbow of colors, have been put to work observing living cells, with possible benefits for medical diagnosis. Read More Read More» Feature E-cigarettes proving to be a danger to teens By Janet Raloff E-cigarettes have surpassed cigarettes as the most commonly used tobacco product among teenagers. Medical researchers are sounding the alarm. Read More Read More» Science Ticker Pluto may have spots the size of Missouri By Christopher Crockett Dark spots emerge on the surface of Pluto in recent images from the New Horizons spacecraft. Read More Read More» News Heat turns wild genetic male reptiles into functional females By Susan Milius Genetic male bearded dragons changed to females by overheating in the wild can still breed successfully. Read More Read More» News in Brief Genetic tweak turned plague bacterium deadly By Sarah Schwartz Two genetic changes allowed plague bacteria to cause deadly lung infections and pandemic disease.  Read More Read More» Culture Beaker Your photos reveal more than where you went on vacation By Rachel Ehrenberg By mining public databases of people’s photos, researchers can explore changing landscapes and tourist behavior. Read More Read More» Sponsor Message More Headlines from Science News News Music to just about everyone’s ears Common elements of music worldwide point to its central role in group cohesion. Read More By Bruce Bower The Science Life In retirement, Nobelist takes up moon bouncing A lifelong amateur radio enthusiast, Joseph Taylor sends signals via the moon. Read More By Julia Rosen Science Ticker Flatworm can self-fertilize by stabbing itself in the head Hermaphroditic flatworms with hypodermic-style mating get sharp with themselves. Read More By Susan Milius Science Ticker Clot-snatching stroke treatment gets the green light Snatching blood clots from the brain with a wire mesh stent is a new stroke treatment that is now supported in the United States. Read More By Ashley Yeager Context Science is heroic, with a tragic (statistical) flaw Science falls short of its own standards because of the mindless use of ritualistic statistical tests. Read More By Tom Siegfried Privacy Policy | Update Email Preferences | Unsubscribe from All SSP Newsletters | Contact Us Facebook | Twitter | YouTube | Google+ Society for Science & the Public • 1719 N Street, N.W. Washington, DC 20036 • Copyright © 2015

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