Weekly News

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Science/AAAS Science

Weekly News
 

08/21/15 Volume 349, Issue 6250

A roundup of the week’s top stories in Science:


Special Section

Special Issue News
Forest Health

Special Issue News
Forest Health

Special Issue News
Forest Health


In Brief

In science news around the world, an animal advocacy group uses crowdsourcing and public records requests to hunt for violations of National Institutes of Health animal research rules; a Global Food Security report warns that climate change will increase weather-related crop disasters; patient advocates and scientists join forces to call for more research into myalgic encephalomyelitis, or chronic fatigue syndrome; and climatologists with the National Oceanic and Atmospheric Administration are forecasting a “Godzilla El Niño” for the winter of 2015 to 2016. Also, scientists link gut microbes to a debilitating eye disease. And new evidence supports the existence of the “exercise” hormone irisin in humans.


In Depth

Energy Development

Between about 850 C.E. and 1250 C.E., Chaco Canyon in northwestern New Mexico’s San Juan Basin was at the center of a vast and sophisticated Pueblo culture. Today, the park is at the center of an oil and gas boom that archaeologists, environmentalists, and Native American activists say threatens a broader landscape filled with hundreds of Chacoan sites. Earlier this month, Chaco experts presented a plan to slow down the granting of drilling leases close to the park. They are also preparing a white paper arguing that the widest possible region around Chaco Canyon should be protected from drilling. Meanwhile, environmental and Native American groups have gone to court to block 239 pending drilling permits in the Chaco area.

Polar Science

The Belgian government and the International Polar Foundation (IPF) are battling for control of Belgium’s €21 research station in Antarctica, the Princess Elisabeth Antarctica. IPF, which built the station and has managed it since its 2009 inauguration, has been accused of misusing public funds. The government says it will run the station from now on, with the help of the Belgian army. But IPF is fighting back; the foundation says it remains in charge. The fight is creating uncertainty for scientists who are preparing for the 2015 to 2016 Antarctic research season.

Animal Welfare

No researchers have applied for required federal permits to conduct invasive research on chimpanzees living in the United States. That suggests that all U.S. biomedical research on chimps has stopped—or is about to stop—and it’s unclear whether the work will ever start again. Research on chimpanzees has been waning since 2013, when the National Institutes of Health (NIH) announced that it would phase out most government-funded chimp research and retire the majority of its research chimps to sanctuaries. The most recent blow came in June, when the U.S. Fish and Wildlife Service stated that all chimpanzees in the United States—including the more than 700 chimps used in research—would be classified as endangered under the Endangered Species Act (ESA). Any labs that wished to continue invasive work on these animals would need to apply for an ESA permit, and the agency would grant permits only for work that enhances the survival of the species and benefits chimpanzees in the wild. By 17 August, however, not a single lab had applied for an ESA permit. And because the agency needs 90 days or more to review permit requests, no labs will have one by the time the rule goes into effect on 14 September. That means any ongoing projects must stop on that date. “This is the beginning of the end of invasive chimpanzee research,” says Stephen Ross, director of the Lester E. Fisher Center for the Study and Conservation of Apes at the Lincoln Park Zoo in Chicago, Illinois, who pushed for the FWS rule. Less clear, however, is whether researchers conducting behavioral studies or other non-invasive research involving chimpanzees will need to obtain a permit.

Energy

This week, Royal Dutch Shell received the federal go-ahead to begin full-scale exploratory drilling in the Chukchi Sea off Northwest Alaska. Since 2010, the company has given more than $15 million to an environmental research program that is jointly managed by the firm’s scientists, outside researchers, and representatives of the native Alaskan Inupiat villages that face the most acute potential environmental impacts from drilling. These studies have focused on ice movements, currents, and the behavior of whales and other animals. Participating scientists have lauded the work as important, but others want environmental research to be conducted by unbiased bodies instead of funded by industry.

Behind the Numbers

This column is the second in a new series that takes a fresh look at some of the numbers that shape policies affecting the scientific community. The first column reexamined a metric devised by the U.S. National Institutes of Health, called the Biomedical Research and Development Price Index, to track the cost of what’s needed to carry out biomedical research. This column tackles the issue of government red tape, specifically, what portion of a grant is devoted to “nonresearch” activities. A closer look at the faculty surveys generating the data suggests there are flaws in the conventional wisdom that scientists are weighted down with a heavy administrative “burden” that interferes with their ability to carry out cutting-edge research.


Feature

Since 2005, when internist Pieter Cohen of the Cambridge Health Alliance in Massachusetts found that his patients were being sickened by a Brazilian weight loss supplement containing antidepressants and thyroid hormones, he has become something of a mix of Indiana Jones and Sherlock Holmes of the supplement world. With chemist colleagues in the United States, Brazil, and Europe, he hunts for drugs illegally buried in supplements. Then he goes public. Ultimately, he hopes to inspire new regulations. So far, Cohen and his collaborators have identified three hidden stimulant drugs in supplements. The discoveries also highlight a broader problem, Cohen and others contend: a dysfunctional system for policing dietary supplements.


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This Week In Science

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Science/AAAS Science

This Week in Science
 

08/21/15 Volume 349, Issue 6250

Editor summaries of this week’s research papers.


This Week in Science

Parasitic Plants

Transcription

Astrophysics

Quantum Gases

Human Impacts

Signal Transduction

Biochemical Processes

Plant Micriobiome

Asthma

Transcription

Population Genetics

RNA Splicing

Ecological Theory

Quantum Simulation

Cancer


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Big insights into dark energy, humans as ‘superpredators’ & hidden dangers of dietary supplements

 

Latest News and Headlines

20 August 2015

 

 

 

Tiny fountain of atoms sparks big insights into dark energy
 

 
 

 

 

Threats impacting forest health
 

 
 

 

 

Feature: Revealing the hidden dangers of dietary supplements
 

 
 

 

 

‘Superpredator’ humans are hunting other animals out of existence
 

 
 

 

 

Special issue: Forest health in a changing world
 

 
 

 

 

Identifying the gene switch that turns fat cells bad
 

 
 

 

 

‘Vomit machine’ shows that norovirus can go airborne
 

 
 

 

 

Stiff breast tissue in obese women may raise cancer risk
 

 
 

 

 

China’s carbon emissions may be 13% lower than estimated
 

 
 

 

 

How Jupiter and Saturn were born from pebbles
 

 
 

 

 

Nominee for DOE science chief looks to better integrate national labs
 

 
 

 

 

A carbon capture strategy that pays
 

 
 

 

 

Watch: Spiders glide gracefully to safety
 

 
 

 

 

 

 
 

 

   

 

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Table of Contents for 21 August 2015; Vol. 349, No. 6250

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Science/AAAS Science

Table of Contents
 

08/21/15 Volume 349, Issue 6250

In this week’s issue:


Special Section

Introduction to Special Issue

Special Issue News
Forest Health

Special Issue News
Forest Health

Special Issue News
Forest Health

Special Issue Review

Special Issue Review

Special Issue Review

Special Issue Review

Special Issue Review


Research Summaries

Editor summaries of this week’s papers.

Highlights of the recent literature.


Editorial


In Brief

A roundup of weekly science policy and related news.


In Depth

Energy Development

Researchers say fracking threatens hundreds of early Pueblo sites and endangers future excavations.

Polar Science

Science at risk in ownership quarrel over Antarctic base.

Animal Welfare

As of 14 September, no U.S. labs will be conducting invasive studies on chimps.

Energy

Critics uneasy at industry role in environmental monitoring.

Behind the Numbers

Many administrative tasks are just part of the job.


Feature

Some dietary supplements are spiked with drugs. Pieter Cohen is out to expose the hazards.


Working Life


Letters


Books et al.

Marine Ecology

Conservation scientist M. Sanjayan prepares to anchor PBS’s first live nature program.

Economics

Economist Anthony Atkinson proposes ambitious policies for combating inequality.

A listing of books received at Science during the week ending 14 August 2015.


Policy Forum

Biosecurity

Is there a foundation of agreement among experts about risk?

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Biotechnology

Forest crises demand regulation and certification reform


Perspectives

Ecology

Effects of human hunting and fishing differ fundamentally from those of other predators [Also see Report by Darimont et al.]

Astrophysics

Fundamental questions about dark matter and dark energy are probed in laboratory experiments [Also see Reports by Hamilton et al. and XENON Collaboration]

Microbiome

A plant defense hormone shapes the root microbiome [Also see Report by Lebeis et al.]

Cell Signaling

Membrane voltage connects lipid organization to cell proliferation [Also see Report by Zhou et al.]

Medicine

A comprehensive strategy to control HCV infection must include a vaccine


Research Articles

Disorder and interactions are tuned to induce nonergodic behavior in an atomic system in a one-dimensional optical lattice.

Genetic variation within ancient and extant Native American populations informs on their migration into the Americas.


Reports

Nuclear magnetic resonance techniques are used to simulate the dynamics of dipolar interactions.

Cold atom experiments can constrain proposed theories of dark energy. [Also see Perspective by Schmiedmayer and Abele]

Results from the XENON100 underground detector set limits on some proposed candidates for dark matter. [Also see Perspective by Schmiedmayer and Abele]

A general model for consumer-resource interactions integrates previous purpose-built models.

Human predators do not mimic the behavior of natural predators. [Also see Perspective by Worm]

Bacteria that are endosymbiotic with the plant root respond to changes in the plant’s signaling status. [Also see Perspective by Haney and Ausubel]

The parasitic weed Striga has given up the secret of its key receptor.

Altered splicing of a splicing regulator activates brain-specific alternative splicing.

Changing the voltage across the plasma membrane causes clustering of a small guanosine triphosphatase. [Also see Perspective by Accardi]

A transcription factor activates gene expression by dramatically changing the shape of promotor DNA.

A regulatory protein factor in bacteria ensures that RNA polymerase stays switched off until it receives the signal to go.


Technical Comments


Podcast

On this week’s show: Human superpredators and a roundup of daily news stories.


New Products

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

 
  Science - Cover
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Science Signaling
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Science Express Notification for 21 August 2015

New Science/AAAS Webinar
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Wednesday, September 2, 2015, at 12 noon Eastern, 9 a.m. Pacific, 5 p.m. UK (BST), 6 p.m. Central Europe (CEST)
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Science/AAAS Science

Science Express
 

08/21/15 Volume 349, Issue 6250

New Science Express articles have been made available:


Research Articles


Reports


New Science/AAAS Webinar
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Wednesday, September 2, 2015, at 12 noon Eastern, 9 a.m. Pacific, 5 p.m. UK (BST), 6 p.m. Central Europe (CEST)
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Cleaning the air with carbon nanofibers, a new cancer risk in obese women & gas giants!

 

Latest News and Headlines

19 August 2015

 

 

 

Identifying the gene switch that turns fat cells bad
 

 
 

 

 

‘Vomit machine’ shows that norovirus can go airborne
 

 
 

 

 

Stiff breast tissue in obese women may raise cancer risk
 

 
 

 

 

Chinas carbon emissions may be 13% lower than estimated
 

 
 

 

 

How Jupiter and Saturn were born from pebbles
 

 
 

 

 

Nominee for DOE science chief looks to better integrate national labs
 

 
 

 

 

A carbon capture strategy that pays
 

 
 

 

 

Watch: Spiders glide gracefully to safety
 

 
 

 

 

How do you weigh an animal that is no more?
 

 
 

 

 

Watch: Hummingbird tongues are tiny pumps
 

 
 

 

 

New U.S. climate rules target methane leaks
 

 
 

 

 

Fourteen percent of U.S. coastline is covered in concrete
 

 
 

 

 

Gut microbes linked to eye disease
 

 
 

 

 

 

 
 

 

   

 

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Latest from Science News: Gene thought to cause obesity works indirectly

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08/20/2015

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Gene thought to cause obesity works indirectly

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Researchers have discovered a “genetic switch” that determines whether people will burn extra calories or save them as fat. Read More

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Contentious science topics on Wikipedia subject to editing mischief

BY Meghan Rosen,

Global warming and other politically charged issues are prime targets for sabotage on Wikipedia. Read More

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‘Vomiting device’ sounds gross but it helps study infections

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Scientists created a “vomiting device” to study how norovirus spreads through the air. Read More

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Sci Transl Med Table of Contents for 19 August 2015; Vol. 7, No. 301

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Science/AAAS Science Translational Medicine

Table of Contents
 

08/19/15 Volume 7, Issue 301


Did you miss?… FOCUS: Single-cell analysis of cancer evolution

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In this week’s issue:


Research Articles

ASTHMA

Concurrent blockade of IL-13 and IL-17A may improve control of asthma.

CANCER

Obesity leads to fibrotic remodeling of mammary adipose tissue, and the resulting increase in interstitial extracellular matrix stiffness promotes breast tumor malignancy.

IMMUNOLOGY

T cell receptor α and β sequences can be accurately paired from hundreds of thousands of T cell clones in parallel.

INFECTIOUS DISEASE

A consensus MERS spike protein synthetic DNA vaccine can induce protective responses against viral challenge.


Focus

ASTHMA

A new T helper cell signature in asthma patients highlights the potential impact of a personalized approach to asthma care (Choy et al., this issue).

TISSUE REMODELING

Obesity promotes breast cancer by enhancing the stiffness of breast adipose tissue through changes in the extracellular matrix (Seo et al., this issue).


Editors’ Choice

METABOLISM

Bile acids activate brown adipose tissue in humans.

THERANOSTICS

New method for sequencing poor-quality RNA–derived formalin-fixed paraffin-embedded tissue should facilitate studies of tumor RNA.

IMMUNE ENGINEERING

Surface-engineered biomaterials and cells mimic the tolerance-promoting properties of regulatory T cells.

BIOMATERIALS

Dense arrays of nanoholes deter cell adhesion and migration.

 
  Science Translational Medicine - Cover

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